Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Influenza virus

Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC88H164N26O19

DescriptionStandard

        RRKKAAVALLAVLLALLA
    

Molecular Weight1890.41 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2088

GRAVY Index1.40

Hydrophobic Moment 0.29

Boman Index0.23

Instability Index41.27

Aliphatic Index 195.56

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 733.86

LogP -2.87

H-bond Donors 27.0

H-bond Acceptors 23.0

Rotatable Bonds 65.0

Heavy Atoms 133.0

Ring Count 0.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157124 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEB peptide analogue

Tax ID32630.0

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antiviral Anti-Influenza

TargetInfluenza virus

Activity1.6 ± 1.2 μM

MethodEC50

RECORD: Rec_0248574 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0250900 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtein-derived synthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-Influenza virus Replication inhibition

TargetInfluenza virus | MDCK cells

Activity3±0 μM

MethodEC50

Half-LifeMammalian: 1 h; Yeast: 2 min; E. coli: 2 min

PaperIdentification of the minimal active sequence of an anti-influenza virus peptide. | Jones JC, Settles EW, Brandt CR, Schultz-Cherry S. | Antimicrob Agents Chemother. 2011 Apr;55(4):1810-3. | DOI:10.1128/AAC.01428-10 | PMID:21220525 PMID21220525 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21220525/