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MYP_120971
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Basic Information
Oncocin [R15,19Orn][I16Tle]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VDKPPYLPRPRPPRXXYNX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0349170 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli 205024
1 μg/mL
MIC
PMID21387510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21387510/
RECORD: Rec_0354132 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae 57 USA
0.5 μg/mL
MIC
PMID21387510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21387510/
RECORD: Rec_0364988 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa DSM 3227
4 μg/mL
MIC
PMID21387510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21387510/
RECORD: Rec_0368489 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X(15)=Orn; X(16)=L-tert-leucine; X(19)=Orn
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
μg/ml
600 μg/mL
Hemolysis
PaperPubMed PMID: 21387510 PMID21387510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21387510/
RECORD: Rec_0370565 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 15,16,19
Bio-Activity Profile
Antimicrobial Antibacterial
Enterobacter cloacae Ha185
0.25 μg/mL
MIC
PMID21387510 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21387510/
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