Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H880N148O164S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTLLDNPGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12213.89 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.07

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index20.57

Aliphatic Index 100.00

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4975.84

LogP -55.25

H-bond Donors 177.0

H-bond Acceptors 173.0

Rotatable Bonds 404.0

Heavy Atoms 859.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002623 VERIFIED: NO

Provenance & Taxonomy

OrganismPicathartes gymnocephalus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria