Peptide Database

Peptide NameLCD278C

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC65H113N17O15S

DescriptionStandard

        QLLIRMIYKNI
    

Molecular Weight1404.76 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.1598

GRAVY Index0.57

Hydrophobic Moment 0.62

Boman Index0.14

Instability Index49.04

Aliphatic Index 177.27

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 548.65

LogP -1.29

H-bond Donors 19.0

H-bond Acceptors 18.0

Rotatable Bonds 49.0

Heavy Atoms 98.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383772 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Integrase inhibition

TargetHeLa

Activity21 μM

MethodIC50

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