Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC474H776N124O133S8

DescriptionStandard

        MKLFLVLIILQFEVPTDTARPRKCFSTITGYCRKKCGIGEIYEMACLNGKLCCVNEDKNKKHKKAPESPHSLPQPDGKIDYVILPTTTLITVQL
    

Molecular Weight10596.50 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.18

Charge Density (pH 7.0) 0.0491

GRAVY Index-0.14

Hydrophobic Moment 0.49

Boman Index0.02

Instability Index41.41

Aliphatic Index 93.30

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4114.83

LogP -34.18

H-bond Donors 145.0

H-bond Acceptors 148.0

Rotatable Bonds 354.0

Heavy Atoms 739.0

Ring Count 15.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209871 VERIFIED: NO

Provenance & Taxonomy

OrganismOdobenus rosmarus divergens [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0211532 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin