Peptide Database

Peptide NameConotoxin-12

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC119H189N41O43S6

DescriptionStandard

        DCGGQGEGCYTQPCCPGLRCRGGGTGGGVCQP
    

Molecular Weight3074.41 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0093

GRAVY Index-0.48

Hydrophobic Moment 0.40

Boman Index0.01

Instability Index33.01

Aliphatic Index 21.25

Aromaticity 0.0312

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1327.41

LogP -22.46

H-bond Donors 50.0

H-bond Acceptors 49.0

Rotatable Bonds 95.0

Heavy Atoms 209.0

Ring Count 4.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092138 VERIFIED: NO

Provenance & Taxonomy

OrganismConus vexillum [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-15; 9-20; 14-30

Bio-Activity Profile

Function

Toxin