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MYP_120839
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Basic Information
Brevibacillin I
Antimicrobial
Standard
13 amino acids
C76H136N16O16
Standard
Sequence
TLKIIVKIVKYLV
Physicochemical Analysis
1529.99 Da
10.00
2.39
2.20
0.1842
1.54
0.72
0.40
-27.85
216.92
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
531.04
1.13
19.0
19.0
53.0
108.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010734 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
T1 dehydrated (Dhb); K3=Orithine, N-terminus is acylated with 2-hydroxy-3-methylvaleric acid (lipo); C-terminus is a characteristic valinol (an alcohol form of valine)
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 159750 or MRSA
2 μg/mL
MIC
PaperBrevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity.
RECORD: Rec_0035456 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
T1 dehydrated (Dhb); K3=Orithine, N-terminus is acylated with 2-hydroxy-3-methylvaleric acid (lipo); C-terminus is a characteristic valinol (an alcohol form of valine)
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii ATCC 17978
64 μg/mL
MIC
PaperBrevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity.
RECORD: Rec_0036963 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
T1 dehydrated (Dhb); K3=Orithine, N-terminus is acylated with 2-hydroxy-3-methylvaleric acid (lipo); C-terminus is a characteristic valinol (an alcohol form of valine)
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa LMG6395
64 μg/mL
MIC
PaperBrevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity.
RECORD: Rec_0367226 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
T1 dehydrated (Dhb); K3=Orithine, N-terminus is acylated with 2-hydroxy-3-methylvaleric acid (lipo); C-terminus is a characteristic valinol (an alcohol form of valine)
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae LMG20218
64 μg/mL
MIC
PaperBrevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity.
RECORD: Rec_0373994 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Lipidation
T1 dehydrated (Dhb); K3=Orithine, N-terminus is acylated with 2-hydroxy-3-methylvaleric acid (lipo); C-terminus is a characteristic valinol (an alcohol form of valine)
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
32 μg/mL
MIC
PaperBrevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity.
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