Peptide Database

Peptide NameB1

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC153H256N42O30

DescriptionStandard

        KFKKLFKKLSPVFKRIVQRIKDFLR
    

Molecular Weight3163.93 Da

Isoelectric Point (pI)11.77

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.54

Charge Density (pH 7.0) 0.3502

GRAVY Index-0.41

Hydrophobic Moment 0.97

Boman Index-0.28

Instability Index20.99

Aliphatic Index 101.20

Aromaticity 0.1600

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1221.39

LogP -4.52

H-bond Donors 44.0

H-bond Acceptors 39.0

Rotatable Bonds 114.0

Heavy Atoms 225.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427256 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

Target218

Activity20 μM

MethodMIC

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