Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length552 amino acids

Chemical FormulaC2628H4125N797O805S21

DescriptionStandard

        MGYRSTNYGRGQALHGDRTTTGAICCSTLPNCTEHGRGVIRVGDKTTACPKCGKQGVVADGEPRVNWMGQTSAVDGSVVICGCPHGTNRVIAPSGEWLGSGPSPEQIAQEKHQAMLAARRKEQEAEAQRQAEERDRNRVFAKSCLRGEGCNDAGTGSEPHTNFAEMAFYQAIPNNALQHAQAAKRKALPKPKQRSALYLWWNGHHEEMDYQAAVAAEERAWTARNAIADASELALVGGRTITSGTWAVRGAALGEIATGGLGAPVAGLLIGMYPGKLNDGEQDFIDRMRAEQMREAPTRVRFTLENDASGNPTPRGWHTPPGKDSVRVRRMEWDSRRQAYTFTTEEDPCITLIWTPDRTGESKPWDTGNHNPVRIPNPVVVDPLPVDTGIGATTSPTPEEKTFADYILILPVGGVPPIYVYIRHNPGQVTGKGQKISGIWLSDANAGNGSPIPSQIADRLRGQTFTDFDQFRKAFWLEVSRDPGLLEQFISNNRASMRKGNAPYTRTPDSVGKRERYEIHHIQPISQGGKVYDVDNMGITTPKHHIKIHKGE
    

Molecular Weight60438.09 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)4.89

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.0089

GRAVY Index-0.64

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index34.78

Aliphatic Index 64.75

Aromaticity 0.0670

Extinction Coeff. Reduced 85370.00

Extinction Coeff. Oxidized 85995.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0101610 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)