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MYP_120779
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Basic Information
(rR)2R4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C48H98N32O9
Standard
Sequence
RRRRRRRR
Physicochemical Analysis
1267.50 Da
12.00
7.76
7.56
0.9700
-4.50
0.27
-2.53
509.95
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
762.22
-10.10
33.0
17.0
47.0
89.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0332876 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Conjugation with liposome
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID24651033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24651033/
RECORD: Rec_0335732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio parahaemolyticus ISP 72-01[20-30% Inhibition = 10 microM]
PMID24243601;26922474 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24243601/
RECORD: Rec_0338944 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23281275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23281275/
RECORD: Rec_0340953 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oligoarginine
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID21359136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21359136/
RECORD: Rec_0346419 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Conjugation with Ahx
Amidation
Ahx, 6-aminohexanoic acid
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25265566 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25265566/
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