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MYP_120779
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Basic Information
(rR)2R4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C48H98N32O9
Standard
Sequence
RRRRRRRR
Physicochemical Analysis
1267.50 Da
12.00
7.76
7.56
0.9700
-4.50
0.27
-2.53
509.95
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
762.22
-10.10
33.0
17.0
47.0
89.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0381442 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
Conjugation with liposome
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25546552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25546552/
RECORD: Rec_0388258 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugated with Cy3-siRNA
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID24969623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24969623/
RECORD: Rec_0388513 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-¦Á-L-lyxo-hexopyranosyl)oxy]-8-(1-hydrazonoethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-Naphthacenedione
Bio-Activity Profile
Anticancer
PaperNew daunomycin¨Coligoarginine conjugates: Synthesis, characterization, and effect on human leukemia and human hepatoma cells Evidence URLhttps://doi.org/10.1002/bip.21264
RECORD: Rec_0392401 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25193363 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25193363/
RECORD: Rec_0394814 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyguanidine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22828784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22828784/
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