Peptide Database

Peptide NameEsculentin-2CG1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC373H609N95O114S6

DescriptionStandard

        MFTMKKSMLLLFFLGTISLSLCEEERSADEDDGEEEVKRSLFSIFKTAAKFVGKNLLKQAGKAGLETLACKAKNEC
    

Molecular Weight8440.78 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0067

GRAVY Index-0.11

Hydrophobic Moment 0.66

Boman Index0.00

Instability Index50.04

Aliphatic Index 83.55

Aromaticity 0.0789

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3408.99

LogP -31.01

H-bond Donors 121.0

H-bond Acceptors 120.0

Rotatable Bonds 301.0

Heavy Atoms 588.0

Ring Count 6.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043380 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops chunganensis [Animal]

FamilyFrog skin active peptide (FSAP); Esculentin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram-negative and Gram-positive bacteria

RECORD: Rec_0087598 VERIFIED: NO