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MYP_120769
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Basic Information
R7I
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C161H289N49O29
Standard
Sequence
IRPIIRPIIRPIIRPIIRPIIRPIIRPI
Physicochemical Analysis
3375.33 Da
12.00
6.76
6.56
0.2414
0.72
0.95
0.09
57.79
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1220.79
-1.48
43.0
36.0
104.0
239.0
7.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010323 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli K88
1 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0016396 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 21630
32 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0027290 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 26305
32 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0039578 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells [Minimum peptide concentration that caused >10% hemolysis (HC10) = >128 microM]
128 μM
Hemolysis
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
RECORD: Rec_0040176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae
2 μM
MIC
PMID30742437 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742437/
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