Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC480H783N127O138S7

DescriptionStandard

        MKLFLVLIILLFEVSKDAARHRKCFSNISGYCRKKCKLGETYEIACVNGKLCCINEDEKRQYQQVTEPPEPSRKPDLKLDYAILPTVTLSTTPL
    

Molecular Weight10765.58 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0376

GRAVY Index-0.24

Hydrophobic Moment 0.62

Boman Index-0.05

Instability Index40.42

Aliphatic Index 94.36

Aromaticity 0.0745

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4287.55

LogP -36.35

H-bond Donors 153.0

H-bond Acceptors 150.0

Rotatable Bonds 362.0

Heavy Atoms 752.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144192 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera acutorostrata scammoni [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0251593 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin