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MYP_120752
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Basic Information
Magainin-2 [S7T,A8L,K10T,F15W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C121H191N31O30S
Standard
Sequence
GIGKFLHTLKTFGKKWVGEIMNS
Physicochemical Analysis
2592.07 Da
10.00
2.85
2.59
0.1237
-0.10
0.62
0.15
-5.40
80.43
0.1304
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
993.15
-6.63
35.0
35.0
89.0
183.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015706 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
35 μM
Hemolysis
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0048145 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 30.4%, E 0.0%, T 43.5%, C 26.1% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0056737 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
15 μM
Paperhttps://pubmed.ncbi.nlm.nih.gov/9335545/ PMID9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9335545/
RECORD: Rec_0120202 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
13 μM
MIC
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0265433 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
13 μM
MIC
PMID9042968;9335545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
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