Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length106 amino acids

Chemical FormulaC557H862N140O153S12

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKFTVAGWFVERCWKNNIGHCRKRCFHIERYKLLCMNKLSCCIPLTSDDPYTQWPIHPTLLEDVTAEFITRDDIPFTPVSGMDDSFTIE
    

Molecular Weight12352.43 Da

Isoelectric Point (pI)5.86

Net Charge (pH 7.0)-2.29

Net Charge (pH 7.4) -2.78

Charge Density (pH 7.0) -0.0216

GRAVY Index0.13

Hydrophobic Moment 0.52

Boman Index0.12

Instability Index44.70

Aliphatic Index 89.15

Aromaticity 0.1132

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4646.05

LogP -33.42

H-bond Donors 168.0

H-bond Acceptors 166.0

Rotatable Bonds 397.0

Heavy Atoms 862.0

Ring Count 24.0

Amide Bonds 110.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0131415 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence