Peptide Database

Peptide NamePyrokinin-4

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC39H62N10O10

DescriptionStandard

        TPFTPRL
    

Molecular Weight830.97 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)0.40

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0569

GRAVY Index-0.36

Hydrophobic Moment 0.39

Boman Index-0.02

Instability Index25.31

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 322.70

LogP -2.37

H-bond Donors 11.0

H-bond Acceptors 11.0

Rotatable Bonds 21.0

Heavy Atoms 59.0

Ring Count 3.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076002 VERIFIED: NO

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0092213 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0117624 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

FamilyPyrokinin

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0391191 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

FamilyPyrokinin

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour