Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC376H594N98O108S11

DescriptionStandard

        MKISFSSILFALMVVFIISSAGNKKMVGEAKDCFQTWTCEGGRKCREKCTAEYKGIGRCDEITAPIVPPQCNCYYPC
    

Molecular Weight8568.05 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)2.43

Net Charge (pH 7.4) 2.07

Charge Density (pH 7.0) 0.0315

GRAVY Index0.03

Hydrophobic Moment 0.49

Boman Index0.07

Instability Index34.90

Aliphatic Index 67.14

Aromaticity 0.1039

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3299.61

LogP -30.84

H-bond Donors 122.0

H-bond Acceptors 122.0

Rotatable Bonds 282.0

Heavy Atoms 593.0

Ring Count 13.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323826 VERIFIED: NO

Provenance & Taxonomy

OrganismBrassica oleracea var. oleracea [Plant]

FamilyDefensin

Tax ID3712

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence