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MYP_120530
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Basic Information
MCoTI-I
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C137H227N49O47S6
Standard
Sequence
GGVCPKILQRCRRDSDCPGACICRGNGYCGSGSD
Physicochemical Analysis
3504.96 Da
8.34
1.71
1.41
0.0502
-0.45
0.68
-0.16
58.45
45.88
0.0294
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1558.66
-24.11
61.0
55.0
114.0
239.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002298 VERIFIED: YES
Provenance & Taxonomy
Momordica cochinchinensis [Plant]
Protease inhibitor I7
3674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic Protease inhibitor Anti-Gram-negative
Pseudomonas aeruginosa
160 μM
MIC
PMID28669767;16336120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0009255 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea cv [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0022786 VERIFIED: YES
Provenance & Taxonomy
Momordica cochinchinensis [Plant]
Protease inhibitor I7
3674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic Protease inhibitor
Human histiocytic lymphoma U-937/GTB
32 μM
IC50
PMID28669767;16336120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0068654 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea cv [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
160 μM
MIC
PMID28669767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
RECORD: Rec_0113094 VERIFIED: YES
Provenance & Taxonomy
Momordica cochinchinensis [Plant]
Protease inhibitor I7
3674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Cytotoxic Protease inhibitor
Candida albicans
160 μM
MIC
PMID28669767;16336120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28669767/
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