Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC486H821N139O144S16

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNWVGKKCANKTGICKKTCKPGEMHAMPAEKMCGKDSVCCVPAKRSGHPSVCVEKKTTRHSTATTTRSLMMNTALMSSMASTPVSVTS
    

Molecular Weight11428.60 Da

Isoelectric Point (pI)9.72

Net Charge (pH 7.0)10.69

Net Charge (pH 7.4) 10.20

Charge Density (pH 7.0) 0.0999

GRAVY Index0.02

Hydrophobic Moment 0.44

Boman Index0.04

Instability Index44.08

Aliphatic Index 65.61

Aromaticity 0.0280

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4510.82

LogP -54.23

H-bond Donors 167.0

H-bond Acceptors 174.0

Rotatable Bonds 385.0

Heavy Atoms 785.0

Ring Count 12.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412479 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence