MYP_120527
Cyclotide mela-6
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Standard
29 amino acids
C131H205N33O41S6
Standard
GLPTCGETCFKGKCYTPGCSCSYPICKKD
3090.62 Da
8.31
1.70
1.40
0.0587
-0.32
0.39
0.00
15.23
26.90
0.1034
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1172.04
-14.19
46.0
49.0
96.0
211.0
6.0
28.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0266062
VERIFIED: YES
Provenance & Taxonomy
Melicytus latifolius [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial
Antibacterial
Anticancer
Cytotoxic
Anti-Gram-negative
Escherichia coli
Qualitative functional evidence
RECORD: Rec_0291525
VERIFIED: YES
Provenance & Taxonomy
Melicytus latifolius [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
human erythrocytes
>64 μM
HC50 / Hemolysis
RECORD: Rec_0296616
VERIFIED: YES
Provenance & Taxonomy
Melicytus latifolius [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic cyclotide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial
Antibacterial
Anticancer
Cytotoxic
Human skin melanoma MM96L
1.58±0.48 μM
IC50
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