Peptide Database

Peptide NamePV reverse-S4(13)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H206N32O22

DescriptionStandard

        VKRKKKPALWKTLLKKVLKA
    

Molecular Weight2377.06 Da

Isoelectric Point (pI)11.51

Net Charge (pH 7.0)8.73

Net Charge (pH 7.4) 8.50

Charge Density (pH 7.0) 0.4363

GRAVY Index-0.58

Hydrophobic Moment 0.66

Boman Index-0.30

Instability Index29.32

Aliphatic Index 117.00

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 913.51

LogP -2.95

H-bond Donors 33.0

H-bond Acceptors 31.0

Rotatable Bonds 87.0

Heavy Atoms 168.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426828 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyDermaseptin

Tax ID8395

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorophore labeling

C-TermAmidation

Other ModsN-term detail: Labelled rhodamine

Bio-Activity Profile

Function

Cell-penetrating peptide Antimicrobial

TargetHeLa

MethodFluorescence-based uptake assay

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