MYP_120457
Basic Information
Cycloviolacin Y5
Antimicrobial
Antiviral
Antiviral Anti-HIV
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Standard
30 amino acids
C132H209N33O42S6
Standard
Sequence
GIPCAESCVWIPCTVTAIVGCSCSDKVCYN
Physicochemical Analysis
3122.66 Da
4.37
-1.30
-1.59
-0.0432
0.82
0.28
0.30
22.25
84.33
0.0667
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1170.52
-13.13
46.0
47.0
93.0
213.0
5.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0041445 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Cyclotide
39648
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antiviral Anti-HIV
HIV
0.04 μM
MIC
RECORD: Rec_0175890 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV
0.04 μM
EC50
RECORD: Rec_0275206 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 10.0%, E 0.0%, T 56.7%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
RECORD: Rec_0338930 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human type A erythrocytes
1.8 μM
IC50