Peptide Database

Peptide NameSLAY-screened peptide P830

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC99H162N24O23S

DescriptionStandard

        PPCPVLLAFPLALARVSPIN
    

Molecular Weight2088.56 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.88

Charge Density (pH 7.0) 0.0474

GRAVY Index1.10

Hydrophobic Moment 0.34

Boman Index0.41

Instability Index66.22

Aliphatic Index 141.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 692.29

LogP -3.04

H-bond Donors 23.0

H-bond Acceptors 25.0

Rotatable Bonds 57.0

Heavy Atoms 147.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235404 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/