Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC420H658N118O122S11

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDTPVAAHQESSKETWMPHFRQKRQSHISLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight9665.15 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0194

GRAVY Index0.07

Hydrophobic Moment 0.57

Boman Index0.06

Instability Index54.79

Aliphatic Index 69.54

Aromaticity 0.0920

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3844.80

LogP -40.94

H-bond Donors 142.0

H-bond Acceptors 138.0

Rotatable Bonds 317.0

Heavy Atoms 671.0

Ring Count 15.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142243 VERIFIED: NO

Provenance & Taxonomy

OrganismCollichthys lucidus [Bacterium]

FamilyHepcidin

Tax ID240159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal