Peptide Database

Peptide NameBasic phospholipase A2 CoaTx-II (svPLA2 homolog) (Lys49 PLA2-like)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC607H954N162O177S16

DescriptionStandard

        SLVELGKMILQETGKNAIPSYGFYGCNCGWGGRGKPKDATDRCCFVHKCCYKKLTDCDPKTDIYSYSWKNKTIICDVNNPCLKEMCECDKAVAICLRENLDTYNKKYRIYPKFLCKKPDTC
    

Molecular Weight13866.09 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)6.41

Net Charge (pH 7.4) 5.89

Charge Density (pH 7.0) 0.0530

GRAVY Index-0.53

Hydrophobic Moment 0.52

Boman Index-0.11

Instability Index29.30

Aliphatic Index 61.24

Aromaticity 0.1074

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23795.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5504.07

LogP -51.82

H-bond Donors 203.0

H-bond Acceptors 201.0

Rotatable Bonds 462.0

Heavy Atoms 962.0

Ring Count 22.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177152 VERIFIED: YES

Provenance & Taxonomy

OrganismCrotalus oreganus abyssus [Animal]

FamilyPhospholipase A2; Group II subfamily; K49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-MRSA Toxin Non-hemolytic

TargetNo Target Organism Found