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MYP_120415
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Basic Information
Agelaia-mastoparan (Agelaia-MP; Insects, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C75H126N18O18
Standard
Sequence
INWLKLGKAIIDAL
Physicochemical Analysis
1567.91 Da
8.59
0.76
0.55
0.0542
0.89
0.59
0.37
-7.50
181.43
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
589.84
-1.02
20.0
19.0
53.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0197587 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative Mast cell degranulation
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0208546 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Mastoparan
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
257 μg/mL
MIC
PMID15225564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15225564/
RECORD: Rec_0226117 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes pallipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
164 μM
MIC
PaperStructural and biological characterization of two novel peptides from the venom of the neotropical social wasp Agelaia pallipes pallipes
RECORD: Rec_0260817 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
237 μg/mL
MIC
PMID15225564;15052574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15225564/
RECORD: Rec_0265435 VERIFIED: YES
Provenance & Taxonomy
Agelaia pallipes pallipes [Animal]
MCD; Mastoparan subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiofilm Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Staphylococcus spp.
PMID15052574;15225564;30974767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15052574/
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