Peptide Database

Peptide Name[I2, K19] ascaphin-8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC91H168N24O23

DescriptionStandard

        GIKDLLKGAAKALVKTVLK
    

Molecular Weight1966.45 Da

Isoelectric Point (pI)10.18

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1977

GRAVY Index0.47

Hydrophobic Moment 0.70

Boman Index0.11

Instability Index-18.85

Aliphatic Index 148.95

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 774.75

LogP -4.51

H-bond Donors 27.0

H-bond Acceptors 27.0

Rotatable Bonds 72.0

Heavy Atoms 138.0

Ring Count 0.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350581 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAscaphin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus multiresistant ATCCBAA-44

Activity6.3 μM

MethodMIC

RECORD: Rec_0355108 VERIFIED: YES