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MYP_120357
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Basic Information
[I2, K19] ascaphin-8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C91H168N24O23
Standard
Sequence
GIKDLLKGAAKALVKTVLK
Physicochemical Analysis
1966.45 Da
10.18
3.76
3.55
0.1977
0.47
0.70
0.11
-18.85
148.95
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
774.75
-4.51
27.0
27.0
72.0
138.0
0.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0063534 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
6.3 μM
MIC
PMID33932712;23094651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33932712/
RECORD: Rec_0167254 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35p
12.5 μM
MIC
PMID33932712;23094651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33932712/
RECORD: Rec_0187807 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
rat RBCs
>800 μM
HC50
PMID33932712;23094651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33932712/
RECORD: Rec_0285478 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
- Escherichia coli ATCC 25922
6.3 μM
MIC
PMID23094651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23094651/
RECORD: Rec_0295909 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ascaphin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
127 μM
MIC
PMID33932712;23094651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33932712/
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