Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length520 amino acids

Chemical FormulaC2523H4033N721O716S16

DescriptionStandard

        MMETGPAMAPGGTAPGGTATACHAPRSRSCPRAEGGLSAPRRPPTGSALALLCLLLLPAACSPATSSSPGIKGRVTQRALEYGRHFGLELLRSQLQKEHELNLQGSYRPPFLGEIQYSVPRIHIQELQMNDSSVGFAEDVGVRLAVRGARIQLSANWSAQLGTFQDSGVVQLHVADLAVAVLLGLSVDEGGRPAVWAAGCDARGTDLHLEFHRGQSWLYNLLVPLFQRTLRQQLNKQLCVELEKSISRMEASLKRMRVSPQLDPFAAIDLSLLGRPDITAEHGDVSLKGEFFGVGRRWQSPFSPKPVGLPEAHEPMVLLALTEFVANSAAFVYFTAGALRRNISGEALPRRFPIQLRTKSLGSFSPQLQELFPDLPMELQLSARRQPLLSCHPDALHGTLYGSAEAFVVLPNTTRAPVFLLDIDANVTGKPTISGNRLGGTVRLTSLSVAQVTSQVGPLQVKKLENVLKFGLWLFGVPWANKRLRSGVPLPTPRGLSLVHPRLSLHEGFMLLATDLQYEP
    

Molecular Weight56435.45 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)10.63

Net Charge (pH 7.4) 9.57

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.05

Hydrophobic Moment 0.74

Boman Index0.07

Instability Index54.05

Aliphatic Index 96.06

Aromaticity 0.0654

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248812 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas zonorhyncha [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria