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MYP_120299
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Basic Information
Defensin ARD1 (Heliomicin analogs; Insects, animals)
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
44 amino acids
C202H306N62O63S6
Standard
Sequence
DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET
Physicochemical Analysis
4803.36 Da
8.32
1.79
1.44
0.0407
-0.42
0.55
-0.03
36.90
44.32
0.1136
13980.00
14355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2045.70
-26.48
78.0
72.0
155.0
333.0
8.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0246258 VERIFIED: YES
Provenance & Taxonomy
Archaeoprepona demophon [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
PaperProtein Sci. 2004 Mar;13(3):703-13. | http://www.ncbi.nlm.nih.gov/pubmed/14978308 PMID14978308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978308/
RECORD: Rec_0247264 VERIFIED: YES
Provenance & Taxonomy
Archaeoprepona demophon [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C. neoformans A
PMID14978308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978308/
RECORD: Rec_0267069 VERIFIED: YES
Provenance & Taxonomy
Archaeoprepona demophon [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans IHEM 8060
6.25 μg/mL
MIC
PMID14978308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978308/
RECORD: Rec_0296690 VERIFIED: NO
Provenance & Taxonomy
Archaeoprepona demophon [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans, Aspergillus fumigatos, Cryptococcus neoformans
RECORD: Rec_0299885 VERIFIED: YES
Provenance & Taxonomy
Archaeoprepona demophon [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
PMID14978308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978308/
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