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MYP_120297
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Basic Information
KLW peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C113H208N28O19
Standard
Sequence
KWKKLLKKLLKLLKKLLK
Physicochemical Analysis
2263.04 Da
10.90
8.75
8.53
0.4862
-0.31
0.84
-0.23
-28.29
173.33
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
807.99
1.89
29.0
28.0
89.0
160.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273426 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16142907/ PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0275894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human ovarian adenocarcinoma SK-OV-3
0.6 μM
IC50
PMID14733952;16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14733952/
RECORD: Rec_0310504 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 55% Hemolysis=100 μM
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0328071 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SK-OV-3
0.6 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
RECORD: Rec_0349104 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SK-MEL-2
0.7 μM
IC50
PMID16142907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16142907/
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