Peptide Database

Peptide NameFMRFamide FMRFa-11

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC46H67N13O13S2

DescriptionStandard

        MDNNFMRF
    

Molecular Weight1074.23 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.71

Charge Density (pH 7.0) -0.0623

GRAVY Index-0.70

Hydrophobic Moment 0.62

Boman Index-0.17

Instability Index-19.46

Aliphatic Index 0.00

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 452.40

LogP -3.73

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 74.0

Ring Count 2.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155472 VERIFIED: NO

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0250174 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyFMRFa

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0349741 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyFMRFamide related peptide

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0368880 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/