Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC454H712N134O136S12

DescriptionStandard

        MKLTRMAVAAAVVIACVCFFQTAAVPFTQQTEDEHRVESETPQENEHLTEISPEQTNPNPLAFFRVKRQSHLSLCRYCCNCCRNRGCGYCCKF
    

Molecular Weight10608.11 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index49.37

Aliphatic Index 59.78

Aromaticity 0.0860

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4366.65

LogP -48.85

H-bond Donors 159.0

H-bond Acceptors 152.0

Rotatable Bonds 344.0

Heavy Atoms 736.0

Ring Count 16.0

Amide Bonds 103.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0140461 VERIFIED: NO

Provenance & Taxonomy

OrganismTor putitora [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence