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MYP_120251
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Basic Information
Temporin-1Cd
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C73H118N14O16
Standard
Sequence
FLPFLASLLSKVL
Physicochemical Analysis
1447.80 Da
8.75
0.76
0.55
0.0584
1.81
0.43
0.59
32.33
180.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
470.21
0.23
16.0
17.0
45.0
103.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176217 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0195985 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0198510 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0300457 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0334301 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 10822101 PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
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