Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC426H673N127O126S8

DescriptionStandard

        MKYFTIVAVFLAVAVCYISQSSASPAPNEEANFVHGADALKQLEPELHGRYKRATCDLLSGTGVGHSACAAHCLLRGNRGGYCNGKGVCVCRN
    

Molecular Weight9846.20 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.25

Charge Density (pH 7.0) 0.0299

GRAVY Index0.05

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index34.85

Aliphatic Index 79.78

Aromaticity 0.0753

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4030.87

LogP -46.33

H-bond Donors 147.0

H-bond Acceptors 141.0

Rotatable Bonds 319.0

Heavy Atoms 687.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017201 VERIFIED: NO

Provenance & Taxonomy

OrganismMusca domestica [Animal]

FamilyDefensin

Tax ID7370

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal