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MYP_120194
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C25H43N5O6
Standard
Sequence
LALPP
Physicochemical Analysis
509.64 Da
5.53
-0.24
-0.44
-0.0480
1.24
0.05
0.60
85.04
176.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
162.14
0.46
4.0
6.0
11.0
36.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279707 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]
9913; 9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins PMID1368548 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368548/
RECORD: Rec_0308745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperKohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.. Inhibition of angiotensin-converting enzyme by synthetic peptides of human b-casein. Agric. Biol. Chem., 53, 2107-2114.
RECORD: Rec_0355807 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 20.0%, C 80.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0376674 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Casein-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
790 μM
IC50
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