Peptide Database

Peptide NameBasic phospholipase A2 BFPA (svPLA2) (EC 3.1.1.4) (Antimicrobial phospholipase A2) (Phosphatidylcholine 2-acylhydrolase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme modulation ▸ Enzyme inhibition ▸ Blood coagulation cascade inhibitor

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC686H1058N188O205S18

DescriptionStandard

        MNPAHLLVLLAVCVSLLGAANIPPQSLNLYQFKNMIQCAGTQLCVAYVKYGCYCGPGGTGTPLDQLDRCCQTHDHCYDNAKKFGNCIPYFKTYEYTCNKPDLTCTDAKGSCARNVCDCDRAAAICFAAAPYNLANFGINKETHCQ
    

Molecular Weight15796.05 Da

Isoelectric Point (pI)7.40

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.00

Charge Density (pH 7.0) 0.0047

GRAVY Index-0.06

Hydrophobic Moment 0.61

Boman Index0.08

Instability Index18.28

Aliphatic Index 71.45

Aromaticity 0.0966

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 14410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6265.43

LogP -68.11

H-bond Donors 224.0

H-bond Acceptors 228.0

Rotatable Bonds 502.0

Heavy Atoms 1097.0

Ring Count 26.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006835 VERIFIED: YES

Provenance & Taxonomy

OrganismBungarus fasciatus [Animal]

FamilyPhospholipase A2; Group I subfamily; D49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Hydrolase Blood coagulation cascade inhibitor Toxin Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0008241 VERIFIED: YES