Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length224 amino acids

Chemical FormulaC1094H1739N271O320S12

DescriptionStandard

        MITQSVEGLERHLQEMKVSFQIDPYVLIEIPLLSAPVVGNSDMELDLKGEFYSARGHPEPPFPAGPFSLAPQEGRMLALGLSEFFFNSAAFAYLAAGLLQVNLTDSMLPKMFPNMLMTVQAFASRPPMVSLQPDNVTVGLSGAAKVFAILPNSSLAPLFTLESEASLDAKAFISDMKLTGSLALRSLTLTLTASEVGEFQTTPLENLLKMEVQAIVLPKVNGRC
    

Molecular Weight24192.91 Da

Isoelectric Point (pI)4.76

Net Charge (pH 7.0)-8.30

Net Charge (pH 7.4) -8.67

Charge Density (pH 7.0) -0.0370

GRAVY Index0.28

Hydrophobic Moment 0.64

Boman Index0.20

Instability Index42.86

Aliphatic Index 100.62

Aromaticity 0.0759

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294785 VERIFIED: NO

Provenance & Taxonomy

OrganismLepisosteus oculatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence