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MYP_120134
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Basic Information
Brevinin-2MS1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C151H253N39O44S2
Standard
Sequence
SFLDKFKDVAIGVAKGAGTGVLKALLCKLDNSC
Physicochemical Analysis
3382.99 Da
8.77
1.44
1.19
0.0436
0.50
0.45
0.18
-2.99
109.39
0.0606
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1340.30
-12.58
48.0
48.0
117.0
236.0
2.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166116 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
150.0 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0186748 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
58.5 % hemolysis at 200 μM
Hemolysis
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0191571 VERIFIED: YES
Provenance & Taxonomy
Hylarana maosuoensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
N. asteroides 201118
9.4 μM
MIC
PaperIdentification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0230748 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae 08040724
75.0 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0263880 VERIFIED: YES
Provenance & Taxonomy
Sylvirana maosonensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa CGMCC 1.50
150.0 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
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