Peptide Database

Peptide NameBeta-defensin 42 (Protein Defb42; rodents, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC459H749N127O115S8

DescriptionStandard

        MRLYLLLSTLLFLLGLLPRVRSGLGAAETHCVNLQGICRRDICKLIEDEIGACRRRWKCCRLWWVLLPIPTPVIFSDYQEPLQTKMK
    

Molecular Weight10143.16 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.54

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0636

GRAVY Index0.23

Hydrophobic Moment 0.72

Boman Index0.06

Instability Index73.02

Aliphatic Index 119.89

Aromaticity 0.0805

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3874.73

LogP -23.93

H-bond Donors 144.0

H-bond Acceptors 130.0

Rotatable Bonds 334.0

Heavy Atoms 709.0

Ring Count 16.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096239 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function