Peptide Database

Peptide NamePotassium channel gamma toxin gamma-KTx 1.9

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC200H312N62O63S9

DescriptionStandard

        DRDSCIDKSRCSKYGYYQECQDCCKKAGHNRGTCMFFKCKCA
    

Molecular Weight4881.58 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.38

Charge Density (pH 7.0) 0.0897

GRAVY Index-0.97

Hydrophobic Moment 0.47

Boman Index-0.34

Instability Index45.39

Aliphatic Index 14.05

Aromaticity 0.1190

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2084.30

LogP -26.17

H-bond Donors 82.0

H-bond Acceptors 77.0

Rotatable Bonds 167.0

Heavy Atoms 334.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250040 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides tecomanus [Animal]

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide5-23; 11-34; 20-39; 24-41

Bio-Activity Profile

Function

Toxin Ion channel blocker