Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length169 amino acids

Chemical FormulaC813H1322N238O240S18

DescriptionStandard

        MRAGGVLTSLRGRAELSWRQMRASRTAATTATLKVFISGGLNCSNWFRALTLVQEKSEELTRVTCTRVKARNQLEQFSPPEMKTFSVAVVAAVLLALICLQESSALPLSELEDVEVPVMDDNGAAVYEEMPVDSWKMPYTNRHKRSPKRCRFCCNCCPRMVGCGTCCKF
    

Molecular Weight18847.81 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.04

Charge Density (pH 7.0) 0.0385

GRAVY Index-0.11

Hydrophobic Moment 0.61

Boman Index-0.04

Instability Index53.65

Aliphatic Index 76.15

Aromaticity 0.0651

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 20105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7711.51

LogP -83.16

H-bond Donors 284.0

H-bond Acceptors 266.0

Rotatable Bonds 624.0

Heavy Atoms 1309.0

Ring Count 23.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343329 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu rubripes [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal