Peptide Database

Peptide NameBig gastrin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC174H257N43O54S

DescriptionStandard

        QLGLQGPPQQVADLSKKQGPWLEEEEAAYGWMDF
    

Molecular Weight3847.22 Da

Isoelectric Point (pI)4.08

Net Charge (pH 7.0)-4.23

Net Charge (pH 7.4) -4.44

Charge Density (pH 7.0) -0.1244

GRAVY Index-0.80

Hydrophobic Moment 0.48

Boman Index0.03

Instability Index75.95

Aliphatic Index 63.24

Aromaticity 0.1176

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1560.58

LogP -12.28

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 124.0

Heavy Atoms 272.0

Ring Count 9.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056442 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyBig gastrin

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Other Mods18:Pyrrolidone carboxylic acid; 29:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0104845 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyGastrin/cholecystokinin