Peptide Database

Peptide NamePACAP-related peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC126H206N36O30S

DescriptionStandard

        IFNKAYRKVLGQLSARKYLHSLM
    

Molecular Weight2737.27 Da

Isoelectric Point (pI)10.56

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.2105

GRAVY Index-0.14

Hydrophobic Moment 0.60

Boman Index-0.05

Instability Index8.82

Aliphatic Index 106.09

Aromaticity 0.1304

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1101.16

LogP -7.48

H-bond Donors 40.0

H-bond Acceptors 37.0

Rotatable Bonds 94.0

Heavy Atoms 193.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083550 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

FamilyPACAP-related peptide

Tax ID8554

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation

Targetits receptor activates G proteins and stimulates adenylate cyclase in pituitary cell

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0084737 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

FamilyPACAP-related peptide

Tax ID8554

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0138715 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0139933 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

FamilyGlucagon

Tax ID8554

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic