Peptide Database

Peptide NameUnnamed

Function Ontology

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC31H55N9O11S2

DescriptionStandard

        QEMKMQ
    

Molecular Weight793.95 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0397

GRAVY Index-1.77

Hydrophobic Moment 0.16

Boman Index-0.44

Instability Index82.20

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 358.32

LogP -3.15

H-bond Donors 11.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 53.0

Ring Count 0.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417931 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHexapeptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermNone

Other ModsN-terminal acetylation

Bio-Activity Profile

Function

Anti-aging miRNA-145 down-regulation Skin stem-cell regulation

TargetHaCaT human keratinocyte cell line (in vitro)

Activity85.50±1.74 %

MethodDirect miRNA-145 quantification assay (relative level vs basal control)

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