Peptide Database

Peptide NamePotassium channel toxin Tx1

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H281N55O47S7

DescriptionStandard

        GVPINVKCRGSRDCLDPCKKAGMRFGKCINSKCHCTP
    

Molecular Weight4023.80 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.1564

GRAVY Index-0.44

Hydrophobic Moment 0.70

Boman Index-0.18

Instability Index33.52

Aliphatic Index 50.00

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1650.50

LogP -20.59

H-bond Donors 63.0

H-bond Acceptors 61.0

Rotatable Bonds 134.0

Heavy Atoms 275.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190068 VERIFIED: YES

Provenance & Taxonomy

OrganismButhus occitanus israelis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

TargetShaker channels

Activity0.0035 ± 0.0005 μM

MethodIC50