Peptide Database

Peptide NameConophysin-R

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC359H549N101O125S17

DescriptionStandard

        HPTKPCMYCSFGQCVGPHICCGPTGCEMGTAEANMCSEEDEDPIPCQVFGSDCALNNPDNIHGHCVADGICCVDDTCTTHLGCL
    

Molecular Weight8824.91 Da

Isoelectric Point (pI)4.23

Net Charge (pH 7.0)-10.92

Net Charge (pH 7.4) -11.60

Charge Density (pH 7.0) -0.1300

GRAVY Index-0.07

Hydrophobic Moment 0.41

Boman Index0.12

Instability Index25.57

Aliphatic Index 51.07

Aromaticity 0.0357

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3494.95

LogP -45.50

H-bond Donors 126.0

H-bond Acceptors 136.0

Rotatable Bonds 273.0

Heavy Atoms 602.0

Ring Count 15.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194551 VERIFIED: YES

Provenance & Taxonomy

OrganismConus radiatus [Animal]

FamilyConophysin-R

Tax ID61198

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-46; 9-20; 14-36; 21-26; 53-71; 65-83; 72-77

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0217139 VERIFIED: YES