Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC546H853N141O158S5

DescriptionStandard

        IKSFFFYLFSPFSFSCSRIHVTAVELPSGSISLLPGSGIKLVIGNASLTIGMNWNIRTWMFKDSGRGTVHISQVFVTAVFSTPLDNAGPMSISLTSCQTTSGDVDIKLNGRT
    

Molecular Weight12080.79 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.92

Net Charge (pH 7.4) 2.57

Charge Density (pH 7.0) 0.0260

GRAVY Index0.34

Hydrophobic Moment 0.54

Boman Index0.22

Instability Index34.04

Aliphatic Index 90.45

Aromaticity 0.1071

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4744.66

LogP -51.19

H-bond Donors 170.0

H-bond Acceptors 168.0

Rotatable Bonds 389.0

Heavy Atoms 850.0

Ring Count 21.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099575 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvietta virens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria