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MYP_119854
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Basic Information
Polyphemusin I [R12-ins]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C114H176N42O22S4
Standard
Sequence
RRWCFRVCYRGRFCYRKCR
Physicochemical Analysis
2615.15 Da
10.83
7.72
7.45
0.4062
-1.03
0.60
-0.67
47.50
15.26
0.2632
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1102.69
-8.79
49.0
34.0
84.0
182.0
6.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007503 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli DC2
0.25 μg/mL
MIC
PMID11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087404/
RECORD: Rec_0047340 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
42.6 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11087404/ PMID11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087404/
RECORD: Rec_0051579 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 21.1%, T 21.1%, C 57.9% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0094329 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus SAP 0017
1 μg/mL
MIC
PMID11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087404/
RECORD: Rec_0109791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus R147
1 μg/mL
MIC
PMID11087404 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087404/
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